"Algunas personas han renunciado tanto a la vida que están dispuestas a conformarse con cualquier cosa."

Simplified Meaning:

Some individuals feel so discouraged or hopeless that they'll accept anything that comes their way, even if it's not good for them. For example, imagine a job situation: someone who has faced many rejections might take a really bad job with terrible pay and awful working conditions because they think they can't do any better. They’ve given up on finding something that makes them happy because they've lost confidence and hope. It's like they've stopped believing they deserve more or that better opportunities are out there. Instead of waiting or fighting for a better chance, they just take whatever they can get, which can lead to unhappiness and feeling stuck. It's important to remember that everyone deserves good things and should keep trying for a better life, no matter how tough it gets.