"Esa es mi lección por tomar unas vacaciones: Las vacaciones te matarán."

Simplified Meaning:

Taking a break or going on vacation can sometimes make you feel more tired or stressed than you were before you left. Imagine you're really busy with work or school, and you're looking forward to a holiday to relax. But instead of feeling refreshed, you come back feeling exhausted and overwhelmed because of all the packing, traveling, and catching up on work. It's like when people go on a trip expecting to rest but end up doing lots of activities that leave them worn out. For example, a person might go on a vacation but spend the whole time rushing from one tourist spot to another, barely sleeping or eating properly. When they get home, they find they are more tired than before and have piles of work waiting for them. This quote suggests that vacationing can sometimes do the opposite of what we expect—it can drain our energy instead of helping us recover. To avoid this, it's better to plan vacations that really let you relax, to avoid over-scheduling, and to prepare for catching up on work when you return.